Prolok 20 mg

Indication

Proton pump inhibitor used to reduce gastric acid secretion. Indicated for gastric and duodenal ulcers, gastro-esophageal reflux disease (GERD), and H. pylori eradication as part of combination therapy.

Ingredients

• Omeprazole 20 mg

Direction

For indication and dosage please see the enclosed leaflet. To be sold on the prescription of a registered physician.

Side effects

• Common: headache
• nausea
• diarrhea
• abdominal pain
• constipation
• flatulence.
• Less common: dizziness
• rash
• peripheral edema
• elevated liver enzymes.
• Rare: hypomagnesaemia
• Clostridioides difficile
• associated diarrhea.
• Very rare: severe skin reactions (Stevens
• Johnson syndrome)
• hepatitis
• interstitial nephritis.

Precautions

• Not recommended in patients with known hypersensitivity to omeprazole or other proton pump inhibitors.
• Exclude gastric malignancy before starting treatment
• may mask symptoms.
• Long
• term use may cause hypomagnesaemia and vitamin B12 deficiency
• periodic monitoring recommended.
• Use with caution in severe hepatic impairment.
• Avoid concomitant use with clopidogrel due to reduced antiplatelet effect.
• May reduce absorption of pH
• dependent drugs (ketoconazole
• itraconazole
• atazanavir).
• Keep out of reach of children.