SETHIKA CARE Pharmacy
Nifedi-Denk 20 Retard 20 mg
Last updated 24/05/2026 at 02:11
Licensed pharmacy partner
SETHIKA CARE Pharmacy
271 Yothapol Khemarak Phoumin Blvd (271), Phnom Penh, Cambodia
Prescription notice
Item may require a valid prescription. Please consult your doctor or pharmacist before using new medication.
Indication
Nifedi-Denk 20 Retard contains Nifedipine in a modified-release (retard) formulation. It is a dihydropyridine calcium channel blocker used to treat hypertension and stable angina pectoris.
Ingredients
- Nifedipine 20 mg (modified
- release)
Direction
Adults: 20 mg twice daily orally, swallowed whole with water. Do not crush or chew the tablet. The dose may be adjusted by a physician up to a maximum of 40 mg twice daily.
Side effects
- Very common: oedema (peripheral
- ankle).
- Common: headache
- dizziness
- flushing
- fatigue.
- Common: nausea
- abdominal discomfort
- constipation.
- Common: palpitations
- tachycardia.
- Uncommon: hypotension
- syncope.
- Rare: gingival hyperplasia.
- Rare: severe skin reactions.
Precautions
- Contraindicated in cardiogenic shock
- acute myocardial infarction (within 4 weeks)
- unstable angina.
- Contraindicated in combination with rifampicin.
- Contraindicated in patients with severe aortic stenosis.
- Avoid grapefruit juice (inhibits CYP3A4 metabolism).
- Use with caution in hepatic impairment.
- Do not abruptly discontinue.
- May cause peripheral oedema.
- Caution with hypotension.
Indication
Nifedi-Denk 20 Retard contains Nifedipine in a modified-release (retard) formulation. It is a dihydropyridine calcium channel blocker used to treat hypertension and stable angina pectoris.
Ingredients
- Nifedipine 20 mg (modified
- release)
Direction
Adults: 20 mg twice daily orally, swallowed whole with water. Do not crush or chew the tablet. The dose may be adjusted by a physician up to a maximum of 40 mg twice daily.
Side effects
- Very common: oedema (peripheral
- ankle).
- Common: headache
- dizziness
- flushing
- fatigue.
- Common: nausea
- abdominal discomfort
- constipation.
- Common: palpitations
- tachycardia.
- Uncommon: hypotension
- syncope.
- Rare: gingival hyperplasia.
- Rare: severe skin reactions.
Precautions
- Contraindicated in cardiogenic shock
- acute myocardial infarction (within 4 weeks)
- unstable angina.
- Contraindicated in combination with rifampicin.
- Contraindicated in patients with severe aortic stenosis.
- Avoid grapefruit juice (inhibits CYP3A4 metabolism).
- Use with caution in hepatic impairment.
- Do not abruptly discontinue.
- May cause peripheral oedema.
- Caution with hypotension.
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