Gastro-Resistant Omeprazole Capsule BP 20 mg Not available

Indication

Treatment of GERD, peptic ulcer, H. pylori eradication, prevention of NSAID-induced ulcers

Ingredients

• Omeprazole 20mg

Direction

Take one capsule once daily before a meal. Swallow whole; do not crush or chew.

Side effects

• Headache
• nausea
• diarrhea
• abdominal pain. Long
• term: vitamin B12 deficiency.

Precautions

• Contraindicated in patients with known hypersensitivity to omeprazole
• other proton pump inhibitors
• or any excipients.
• Exclude malignancy before treating gastric symptoms
• as omeprazole may mask symptoms of gastric cancer.
• Long
• term use (more than 1 year) is associated with increased risk of bone fractures (hip
• wrist
• spine)
• consider calcium and vitamin D supplementation in at
• risk patients.
• Proton pump inhibitors may increase the risk of Clostridium difficile
• associated diarrhoea.
• Hypomagnesaemia has been reported with prolonged use
• monitor magnesium levels in patients on long
• term therapy or taking digoxin or medications known to cause hypomagnesaemia.
• May reduce the efficacy of clopidogrel
• avoid concomitant use if possible.
• Reduces absorption of drugs dependent on gastric acidity (e.g.
• ketoconazole
• itraconazole
• erlotinib
• iron salts
• vitamin B12).
• Use with caution in patients with severe hepatic impairment
• dose adjustment may be required.
• Subacute cutaneous lupus erythematosus (SCLE) has been reported rarely
• discontinue if SCLE occurs.
• Keep out of reach of children.