Duphalac 10 g/15 mL

Indication

Symptomatic treatment of constipation; adjunct treatment of hepatic encephalopathy.

Ingredients

• Lactulose

Direction

Adults (constipation): 15–45 mL (10–30 g) daily, adjusted to produce soft stools. Elderly: 15–30 mL daily. Children over 14 years: same as adults. Hepatic encephalopathy: 30–50 mL three times daily. May be taken undiluted or mixed with water or juice. Effect usually occurs within 24–48 hours.

Side effects

• Common: bloating
• flatulence
• abdominal discomfort (especially at start of treatment).
• At high doses: diarrhea
• nausea
• vomiting.
• Long
• term high
• dose use may cause electrolyte imbalance (hypokalemia
• hypernatremia).

Precautions

• Contraindicated in patients with galactosaemia
• or obstruction of the gastrointestinal tract.
• Use with caution in patients who are lactose intolerant (contains small amounts of lactose and galactose).
• Diabetic patients should be aware of the sugar content.
• Prolonged use should be under medical supervision.
• Consult a doctor before use in pregnancy.
• Keep out of reach of children.