Zomep-20 20 mg

Indication

Proton pump inhibitor for treatment of gastric and duodenal ulcers, gastro-esophageal reflux disease (GERD), Zollinger-Ellison syndrome, and as part of H. pylori eradication regimens.

Ingredients

• Omeprazole 20 mg

Direction

As directed by the physician.

Side effects

• Common: headache
• nausea
• diarrhea
• abdominal pain
• constipation
• flatulence.
• Less common: dizziness
• rash
• peripheral edema
• elevated liver enzymes.
• Rare: hypomagnesaemia
• Clostridioides difficile
• associated diarrhea with prolonged use.
• Very rare: severe skin reactions (Stevens
• Johnson syndrome)
• hepatitis
• interstitial nephritis.

Precautions

• Not recommended for patients with known hypersensitivity to omeprazole or other proton pump inhibitors.
• Exclude gastric malignancy before initiating treatment
• omeprazole may mask symptoms.
• Long
• term use may lead to hypomagnesaemia and vitamin B12 deficiency
• monitor electrolytes.
• Use with caution in patients with severe hepatic impairment.
• May interact with clopidogrel by reducing its antiplatelet effect
• avoid concomitant use where possible.
• Reduces absorption of drugs requiring acidic pH (e.g.
• ketoconazole
• itraconazole
• atazanavir).
• Keep out of reach of children.