Esome 40 mg

Indication

Proton pump inhibitor used to reduce gastric acid. Indicated for gastro-esophageal reflux disease (GERD), erosive esophagitis, peptic ulcer disease, and as part of H. pylori eradication therapy.

Ingredients

• Esomeprazole 40 mg

Direction

See package insert for full prescribing information or as directed by the physician.

Side effects

• Common: headache
• nausea
• diarrhea
• abdominal pain
• constipation
• flatulence.
• Less common: dizziness
• dry mouth
• peripheral edema
• elevated liver enzymes.
• Rare: hypomagnesaemia with prolonged use
• Clostridioides difficile
• associated diarrhea.
• Very rare: severe skin reactions (Stevens
• Johnson syndrome)
• hepatitis
• interstitial nephritis.

Precautions

• Not recommended in patients with hypersensitivity to esomeprazole
• other proton pump inhibitors
• or any benzimidazole.
• Exclude gastric malignancy before treatment
• esomeprazole may mask symptoms.
• Long
• term use associated with hypomagnesaemia and vitamin B12 deficiency
• periodic monitoring recommended.
• Use with caution in severe hepatic impairment
• dose reduction required.
• May reduce efficacy of clopidogrel
• avoid concomitant use where possible.
• May reduce absorption of pH
• dependent drugs (ketoconazole
• itraconazole
• atazanavir
• erlotinib).
• Keep out of reach of children.