Dexamethasone Medigrow 4mg/ml

Indication

Dexamethasone Medigrow injection (4 mg/mL) is a synthetic corticosteroid used parenterally for the treatment of acute conditions requiring rapid anti-inflammatory or immunosuppressive effect, including cerebral oedema, anaphylaxis, severe allergic reactions, asthma exacerbations, croup, septic shock (adjunct), and as anti-emetic prophylaxis in chemotherapy.

Ingredients

• Dexamethasone Phosphate

Direction

Adults: 0.5–9 mg IV or IM per dose depending on indication and severity. Cerebral oedema: 10 mg IV bolus, then 4 mg IM every 6 hours. Doses are highly indication-specific; always follow physician or institution protocol. Adjust dose in the elderly and in renal/hepatic impairment.

Side effects

• Hyperglycaemia.
• Sodium and fluid retention
• hypokalaemia.
• Hypertension.
• Increased infection susceptibility.
• Adrenal suppression.
• Gastrointestinal haemorrhage with high doses.
• Mood changes
• insomnia.

Precautions

• Prolonged use suppresses the HPA axis — taper gradually.
• Increases susceptibility to infections
• may mask signs of infection.
• Contraindicated in systemic fungal infections.
• Use with caution in diabetes
• hypertension
• heart failure
• and osteoporosis.
• Avoid live vaccines during treatment.
• Benzyl alcohol (common preservative in vials) is toxic in neonates.
• Keep out of reach of children.