Coveram 5 mg / 5 mg

Indication

Coveram 5 mg/5 mg is a fixed-dose combination antihypertensive used for the treatment of essential hypertension in adults whose blood pressure is not adequately controlled on either component alone.

Ingredients

• perindopril arginine
• amlodipine

Direction

Adults: 1 tablet once daily, preferably in the morning before a meal. The dose must be titrated by a physician based on blood pressure response.

Side effects

• Dry persistent cough (ACE inhibitor class effect).
• Headache
• dizziness
• and flushing.
• Peripheral oedema.
• Palpitations.
• Hypotension.
• Rare: angioedema.

Precautions

• Contraindicated in patients with hypersensitivity to perindopril (or other ACE inhibitors)
• amlodipine
• or history of ACE inhibitor
• induced angioedema.
• Contraindicated during second and third trimester of pregnancy.
• Monitor renal function
• serum potassium
• and blood pressure.
• Risk of hypotension
• especially on first dose.
• Use with caution in renal artery stenosis or severe hepatic impairment.
• Keep out of reach of children.