Coversyl 5 mg

Indication

Coversyl 5 mg is an ACE inhibitor used for the treatment of essential hypertension, symptomatic heart failure, and stable coronary artery disease (to reduce risk of cardiac events in patients with a history of myocardial infarction or coronary revascularisation).

Ingredients

• perindopril arginine

Direction

Hypertension (adults): Initially 5 mg once daily in the morning; may increase to 10 mg once daily after 1 month if tolerated. Heart failure: Initially 2.5 mg once daily; titrated up to 5 mg. Take before food.

Side effects

• Dry persistent cough.
• Headache and dizziness.
• Hypotension.
• Hyperkalaemia.
• Impaired renal function.
• Rare: angioedema (potentially life
• threatening — discontinue immediately).

Precautions

• Contraindicated in patients with history of ACE inhibitor
• induced angioedema.
• Contraindicated during second and third trimester of pregnancy.
• Contraindicated with aliskiren in patients with diabetes or renal impairment.
• May cause first
• dose hypotension especially in volume
• depleted patients.
• Monitor renal function and potassium
• especially with concomitant diuretics.
• Dry cough is a class effect — consider switching to ARB if intolerable.
• Keep out of reach of children.