Ceftriaxone Sodium for Injection 1 g

Indication

Ceftriaxone Sodium for Injection (1 g) is a third-generation cephalosporin antibiotic for parenteral use. Indicated for treatment of severe bacterial infections including septicaemia, meningitis, pneumonia, intra-abdominal infections, complicated UTIs, pelvic inflammatory disease, skin and soft tissue infections, bone and joint infections, and surgical prophylaxis.

Ingredients

• Ceftriaxone Sodium

Direction

Adults: 1–2 g once daily IV or IM. Meningitis and severe infections: 2–4 g once daily. Children: 50–100 mg/kg/day (max 4 g/day). Administer as directed by a healthcare professional. Reconstitute according to manufacturer instructions.

Side effects

• Injection site pain and phlebitis.
• Diarrhoea
• nausea.
• Skin rash and eosinophilia.
• Biliary sludge.
• Rare: severe allergic reactions
• haemolytic anaemia
• pseudomembranous colitis.

Precautions

• Contraindicated in known hypersensitivity to ceftriaxone or other cephalosporins.
• Cross
• sensitivity with penicillins — use with caution in penicillin
• allergic patients.
• Do not mix with calcium
• containing IV solutions — risk of precipitation.
• Contraindicated in neonates under 28 days with hyperbilirubinaemia or on calcium
• containing IV infusions.
• Monitor renal and hepatic function in prolonged use.
• Monitor for Clostridioides difficile
• associated diarrhoea.
• Keep out of reach of children.