Omez 20 mg

Indication

Omeprazole is a proton pump inhibitor (PPI) used to treat gastroesophageal reflux disease (GERD), peptic ulcer disease, erosive esophagitis, Zollinger-Ellison syndrome, and as part of combination therapy for Helicobacter pylori eradication.

Ingredients

• Omeprazole

Direction

Adults: 20 mg once daily before a meal, typically in the morning, for 4–8 weeks. For H. pylori eradication, doses and duration are prescribed in combination with antibiotics. Swallow capsule whole; do not crush or chew.

Side effects

• Headache.
• Nausea
• diarrhea
• abdominal pain.
• Flatulence
• constipation.
• Rash.
• Elevated liver enzymes (rare).
• With long
• term use: hypomagnesemia
• increased fracture risk.

Precautions

• Use with caution in patients with severe liver impairment.
• Long
• term use (>1 year) may be associated with hypomagnesemia and vitamin B12 deficiency.
• May increase risk of Clostridium difficile
• associated diarrhea.
• May reduce absorption of drugs dependent on gastric pH (e.g.
• ketoconazole
• atazanavir).
• Symptomatic response does not preclude gastric malignancy
• investigate if symptoms persist.
• Pregnancy category C
• use only if clearly needed.