NHU-D8 Diffelene 15 g - ឱសថស្ថាន សិរីមង្គលថ្មី
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Last updated 28/08/2026 at 5:12 PM

Indication

NHU-D8 Diffelene (Adapalene 0.1% gel/cream, 15 g) is a topical retinoid used for the treatment of mild to moderate acne vulgaris. It normalises follicular keratinisation, reduces comedone formation, and has anti-inflammatory properties.

Ingredients
  • Adapalene
Direction

Adults and adolescents: Apply a thin layer to the affected skin area once daily at bedtime, after cleansing and drying the face. Avoid the eyes, lips, and mucous membranes. Use a sunscreen during the day as adapalene increases photosensitivity.

Side effects
  • Skin dryness
  • peeling
  • or flaking
  • Redness or erythema at application site
  • Burning or stinging sensation
  • Worsening of acne in the initial weeks (purging phase)
  • Photosensitivity
Precautions
  • Avoid contact with eyes
  • lips
  • and mucous membranes.
  • Do not apply to sunburned
  • eczematous
  • or broken skin.
  • Increased sensitivity to sunlight
  • apply sunscreen and limit UV exposure.
  • Initial dryness
  • redness
  • or peeling may occur
  • reduce frequency if severe.
  • Contraindicated during pregnancy (retinoid — teratogenic risk).
  • Do not use with other retinoids concurrently.
  • Keep out of reach of children.

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