Primodil-AT Not available

Indication

Primodil-AT (Amlodipine + Atenolol) is a fixed-dose combination antihypertensive. Amlodipine is a calcium channel blocker and Atenolol is a cardioselective beta-blocker. The combination is used to treat hypertension and stable angina pectoris, providing complementary mechanisms to reduce blood pressure and cardiac workload.

Ingredients

• Amlodipine
• Atenolol

Direction

Adults: 1 tablet once daily, with or without food, as directed by a physician. Do not stop taking abruptly, especially the atenolol component.

Side effects

• Peripheral oedema
• flushing (amlodipine)
• Bradycardia
• fatigue
• cold extremities (atenolol)
• Dizziness
• headache
• Nausea
• Bronchospasm (atenolol — in susceptible patients)

Precautions

• Do not stop abruptly — may precipitate angina or rebound hypertension.
• Contraindicated in cardiogenic shock
• sick sinus syndrome
• second or third degree AV block
• uncompensated heart failure
• and severe bradycardia.
• Use with caution in diabetic patients (atenolol may mask hypoglycaemia signs).
• Use with caution in asthmatic or COPD patients (beta
• blocker may worsen bronchoconstriction).
• Use with caution in patients with severe hepatic impairment (amlodipine).
• May cause peripheral oedema (amlodipine).
• Keep out of reach of children.