Lopid 300mg

Indication

Gemfibrozil 300 mg is a fibrate lipid-regulating agent used to reduce elevated triglyceride levels in patients with hypertriglyceridaemia and to increase HDL cholesterol, as adjunct therapy to dietary measures.

Ingredients

• Gemfibrozil

Direction

Adults: The usual dose is 300 mg twice daily (600 mg total), taken 30 minutes before morning and evening meals. Full dose is 1200 mg/day in two divided doses of 600 mg each (standard schedule); adjust per physician's prescription as 300 mg capsules require 2 capsules per dose.

Side effects

• Gastrointestinal upset (dyspepsia
• nausea
• diarrhoea
• abdominal pain).
• Headache
• dizziness.
• Muscle pain (myalgia).
• Rare: cholelithiasis (gallstones)
• myopathy
• rhabdomyolysis.
• Rare: elevated liver enzymes.

Precautions

• Contraindicated in severe renal or hepatic impairment
• pre
• existing gallbladder disease
• and in combination with repaglinide.
• Risk of myopathy or rhabdomyolysis
• especially in combination with statins — avoid concurrent use where possible.
• Increases the anticoagulant effect of warfarin
• monitor INR closely.
• Regular liver function and full blood count monitoring recommended.
• Keep out of reach of children.