Gabica 75mg

Indication

Pregabalin is used to treat neuropathic pain (nerve pain) associated with diabetic peripheral neuropathy, post-herpetic neuralgia, and spinal cord injury. It is also used as adjunctive therapy for partial-onset seizures in adults and for the treatment of generalised anxiety disorder (GAD) and fibromyalgia.

Ingredients

• Pregabalin 75mg

Direction

Adults: The usual starting dose is 75 mg twice daily or 50 mg three times daily. Dose may be increased to 150 mg twice daily (300 mg/day) after 1 week based on efficacy and tolerability. Maximum dose is 600 mg/day. Take with or without food. Swallow whole with water. Dose must be adjusted in renal impairment. Not indicated for use in children under 18 years for most indications.

Side effects

• Dizziness (very common).
• Somnolence / drowsiness (very common).
• Headache.
• Blurred or double vision.
• Weight gain.
• Peripheral oedema (swelling of hands and feet).
• Dry mouth.
• Constipation.
• Nausea.
• Ataxia (impaired coordination).
• Memory impairment or difficulty concentrating.
• Mood changes
• euphoria
• confusion.
• Increased risk of suicidal ideation (rare but serious).

Precautions

• Do not stop abruptly — taper dose gradually to avoid withdrawal symptoms (insomnia
• nausea
• headache
• anxiety).
• Use with caution in patients with renal impairment
• dose adjustment required.
• May cause dizziness and somnolence — avoid driving or operating machinery until effect is known.
• Caution in patients with a history of substance abuse.
• May increase risk of suicidal thoughts or behaviour
• monitor closely.
• Caution in patients with congestive heart failure.
• Avoid alcohol — additive CNS depression.
• Use in pregnancy only if clearly needed
• risk to foetus not fully established.
• Pregabalin passes into breast milk
• avoid breastfeeding or discontinue drug.