Cardlife-Extra 40 mg / 10 mg

Indication

Treatment of essential hypertension in adults whose blood pressure is not adequately controlled with olmesartan medoxomil or amlodipine alone. Fixed-dose combination of an angiotensin II receptor antagonist (Olmesartan) and a calcium channel blocker (Amlodipine).

Ingredients

• Olmesartan medoxomil USP 40 mg
• Amlodipine besylate USP equivalent to Amlodipine 10 mg

Direction

As directed by the physician. Take 1 tablet once a day. The dosage may be increased up to 2 tablets in a day if required. Do not take more than 2 tablets in 24 hours.

Side effects

• Common: dizziness
• headache
• peripheral oedema
• palpitations
• flushing
• fatigue.
• Less common: nausea
• abdominal pain
• rash
• sprue
• like enteropathy (with chronic olmesartan use)
• tachycardia.
• Rare but serious: angioedema
• acute renal failure
• severe hyperkalaemia
• hepatic dysfunction.
• Stop use and seek medical attention immediately for swelling of the face
• lips or tongue
• severe rash
• fainting
• chest pain or persistent severe diarrhoea.

Precautions

• Prescription
• only — use only under medical supervision.
• Do not use in pregnancy (especially in the 2nd and 3rd trimesters) or breastfeeding.
• Do not use in known hypersensitivity to olmesartan
• amlodipine
• dihydropyridines or any of the excipients.
• Use with caution in patients with severe aortic stenosis
• severe hypotension
• recent myocardial infarction
• unstable angina
• severe hepatic impairment
• renal artery stenosis or volume depletion.
• Monitor renal function
• serum potassium and blood pressure periodically.
• Co
• administration with potassium
• sparing diuretics
• potassium supplements or salt substitutes containing potassium is generally not recommended.