Promet-400 400 mg

Indication

Reduces gastric acid secretion. Treatment of duodenal ulcer, benign gastric ulcer, gastro-oesophageal reflux disease (GERD), and prevention of stress-related upper gastrointestinal bleeding. Also used in management of Zollinger-Ellison syndrome.

Ingredients

• Cimetidine

Direction

Adults: usually 400 mg twice a day (with breakfast and at bedtime), or 800 mg once a day at bedtime, for at least 4 to 6 weeks for active ulcer treatment. Maintenance dose 400 mg at bedtime. Dosage should be adjusted by the prescribing physician based on indication and renal function.

Side effects

• May include headache
• dizziness
• diarrhoea
• fatigue
• skin rash
• and gynaecomastia (with prolonged high
• dose use). Rare side effects include confusion (especially in elderly or renal impairment) and reversible liver enzyme changes. Stop use and consult a doctor or pharmacist immediately if you experience any unusual or severe reaction.

Precautions

• Prescription
• only medicine. Use under medical supervision. Inform your doctor of any kidney or liver impairment
• pregnancy
• or breastfeeding. Cimetidine can interact with many drugs (warfarin
• phenytoin
• theophylline
• beta
• blockers
• etc.) — review concurrent medications with a pharmacist. Long
• term use should be reviewed periodically. Symptomatic response does not preclude the presence of gastric malignancy.