Advant 8 8 mg

Indication

Advant 8 contains Candesartan cilexetil, an angiotensin II receptor blocker (ARB) used to treat hypertension and heart failure in adults.

Ingredients

• Candesartan cilexetil 8 mg

Direction

Adults: For hypertension, 8 mg once daily initially; may be increased to 16–32 mg once daily. For heart failure, start at 4 mg once daily and titrate under medical supervision. Take with or without food.

Side effects

• Common: dizziness
• headache.
• Common: respiratory infections.
• Uncommon: hypotension
• renal impairment
• hyperkalaemia.
• Uncommon: nausea
• diarrhoea.
• Rare: angioedema (stop immediately and seek emergency care).
• Very rare: leukopenia
• neutropenia.

Precautions

• Contraindicated in pregnancy (2nd and 3rd trimesters) and breastfeeding.
• Contraindicated in severe hepatic impairment or biliary obstruction.
• Do not combine with aliskiren in diabetic patients.
• Monitor serum potassium and renal function.
• Risk of hyperkalaemia especially with potassium
• sparing diuretics.
• Risk of hypotension in volume
• or sodium
• depleted patients.
• Caution in renal impairment.