Rovista 10 10 mg

Indication

Rovista 10 contains Rosuvastatin, an HMG-CoA reductase inhibitor (statin) used to treat primary hypercholesterolaemia, mixed dyslipidaemia, and to reduce cardiovascular events. It reduces LDL-cholesterol, total cholesterol, and triglycerides while raising HDL-cholesterol.

Ingredients

• Rosuvastatin 10 mg

Direction

Adults: 5–10 mg once daily orally. Dose may be increased at 4-week intervals to a maximum of 40 mg/day in high-risk patients. Take at any time of day, with or without food. Swallow the tablet whole.

Side effects

• Common: headache
• myalgia
• nausea
• abdominal pain
• constipation.
• Common: dizziness
• asthenia.
• Uncommon: myopathy.
• Rare: rhabdomyolysis (stop immediately).
• Rare: hepatitis
• proteinuria
• haematuria.
• Very rare: interstitial lung disease with long
• term use.
• Rare: new
• onset diabetes mellitus.

Precautions

• Contraindicated in active liver disease or unexplained elevation of serum transaminases.
• Contraindicated in pregnancy and breastfeeding.
• Maximum dose 20 mg in Asian patients (due to higher systemic exposure).
• Risk of myopathy and rhabdomyolysis — report muscle pain or weakness immediately.
• Monitor renal function in patients at risk.
• Caution with ciclosporin
• warfarin (monitor INR)
• fibrates
• and niacin.
• Reduce dose in moderate renal impairment
• contraindicated in severe renal impairment.