SETHIKA CARE Pharmacy
Glucophage 850 mg
Last updated 24/05/2026 at 02:11
Licensed pharmacy partner
SETHIKA CARE Pharmacy
271 Yothapol Khemarak Phoumin Blvd (271), Phnom Penh, Cambodia
Prescription notice
Item may require a valid prescription. Please consult your doctor or pharmacist before using new medication.
Indication
Glucophage (metformin) is a biguanide antidiabetic agent used for the management of type 2 diabetes mellitus in adults and children over 10 years. It reduces hepatic glucose production and improves insulin sensitivity.
Ingredients
- Metformin Hydrochloride 850 mg (film
- coated tablet)
Direction
Adults: initially 500 mg or 850 mg once or twice daily with meals; increase gradually. Usual maintenance: 1500–2000 mg/day in 2–3 divided doses; maximum 3000 mg/day. Take with or immediately after food to reduce GI side effects.
Side effects
- Nausea
- vomiting
- diarrhea
- and abdominal discomfort (common
- especially at initiation
- take with food to reduce).
- Metallic taste.
- Lactic acidosis (rare but serious).
- Vitamin B12 deficiency with prolonged use.
- Hypoglycaemia does not occur with metformin alone.
Precautions
- Do not use in patients with severe renal impairment (eGFR <30 mL/min)
- hepatic impairment
- or conditions causing hypoxia (heart failure
- respiratory failure).
- Hold metformin 48 hours before and after contrast media procedures.
- Do not use in patients with diabetic ketoacidosis.
- Alcohol increases the risk of lactic acidosis.
- Monitor renal function regularly.
- Keep out of reach of children.
Indication
Glucophage (metformin) is a biguanide antidiabetic agent used for the management of type 2 diabetes mellitus in adults and children over 10 years. It reduces hepatic glucose production and improves insulin sensitivity.
Ingredients
- Metformin Hydrochloride 850 mg (film
- coated tablet)
Direction
Adults: initially 500 mg or 850 mg once or twice daily with meals; increase gradually. Usual maintenance: 1500–2000 mg/day in 2–3 divided doses; maximum 3000 mg/day. Take with or immediately after food to reduce GI side effects.
Side effects
- Nausea
- vomiting
- diarrhea
- and abdominal discomfort (common
- especially at initiation
- take with food to reduce).
- Metallic taste.
- Lactic acidosis (rare but serious).
- Vitamin B12 deficiency with prolonged use.
- Hypoglycaemia does not occur with metformin alone.
Precautions
- Do not use in patients with severe renal impairment (eGFR <30 mL/min)
- hepatic impairment
- or conditions causing hypoxia (heart failure
- respiratory failure).
- Hold metformin 48 hours before and after contrast media procedures.
- Do not use in patients with diabetic ketoacidosis.
- Alcohol increases the risk of lactic acidosis.
- Monitor renal function regularly.
- Keep out of reach of children.
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