Simnac Plus 500 mg / 100 mg / 15 mg

Indication

Prescription anti-inflammatory and analgesic combination for the relief of pain, inflammation and swelling in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, low back pain, musculoskeletal injuries and sprains, post-operative and dental pain, and soft-tissue inflammation; the paracetamol component also reduces fever.

Ingredients

• Paracetamol BP 500 mg
• Aceclofenac BP 100 mg
• Serratiopeptidase 15 mg (30
• 000 units
• as enteric
• coated granules)

Direction

Oral route, as directed by the physician. Usual adult dose: 1 tablet twice daily after meals, swallowed whole with water; do not crush or chew. Do not exceed the prescribed dose or duration.

Side effects

• Nausea
• indigestion
• heartburn or abdominal pain
• Diarrhoea or constipation
• Dizziness or headache
• Skin rash or itching
• Raised liver enzymes
• Rarely
• stomach ulcer or gastrointestinal bleeding (black stools
• vomiting blood) or severe allergic reaction
• stop use and seek medical help

Precautions

• Prescription medicine
• use only under medical supervision
• Do not use if allergic to aceclofenac
• diclofenac
• paracetamol
• aspirin or other NSAIDs
• or with active peptic ulcer or gastrointestinal bleeding
• Do not take with other paracetamol
• containing products or other NSAIDs
• overdose of paracetamol may cause serious liver damage
• Use with caution in liver
• kidney or heart disease
• hypertension
• asthma or bleeding disorders
• and in the elderly
• avoid alcohol
• Use with caution with anticoagulants
• as serratiopeptidase and NSAIDs may increase bleeding risk
• Consult a doctor or pharmacist before use if pregnant or breastfeeding
• avoid in late pregnancy
• Keep out of reach of children