Seretide Evohaler 25 mcg / 125 mcg per actuation (120 actuations)

Indication

Regular, twice-daily maintenance treatment to prevent asthma symptoms such as breathlessness and wheezing. Combines salmeterol, a long-acting bronchodilator that keeps the airways open for at least 12 hours, with fluticasone propionate, a corticosteroid that reduces swelling and irritation in the lungs. Not for relief of a sudden asthma attack; use a fast-acting reliever inhaler (such as salbutamol) for that.

Ingredients

• Salmeterol (as salmeterol xinafoate) 25 mcg per actuation
• Fluticasone propionate 125 mcg per actuation
• Propellant: norflurane (HFA 134a)

Direction

Adults and adolescents 12 years and over: 2 puffs twice a day, inhaled through the mouth, every day as prescribed. Shake the inhaler before each puff, breathe out, close the lips around the mouthpiece and press the canister while breathing in slowly and deeply, then hold the breath for a few seconds. Wait about 30 seconds between puffs. Rinse the mouth with water and spit out after use. Test-fire before first use. Do not stop or reduce the dose without your doctor.

Side effects

• Very common: headache.
• Common: thrush in the mouth and throat
• hoarse voice
• throat irritation
• aching or swollen joints
• muscle pain
• muscle cramps
• in COPD patients pneumonia
• bronchitis
• sinusitis
• bruising and low blood potassium have been reported.
• Uncommon: raised blood sugar
• cataract
• fast or uneven heartbeat
• tremor
• chest pain
• anxiety
• disturbed sleep
• allergic skin rash.
• Stop and seek help at once if breathing suddenly gets worse after use or if you get swelling of the face
• lips
• tongue or throat.

Precautions

• Do not use if allergic to salmeterol
• fluticasone propionate or norflurane.
• Not for treating a sudden asthma attack
• always carry your fast
• acting reliever inhaler.
• Tell your doctor if you have heart disease or irregular heartbeat
• overactive thyroid
• high blood pressure
• diabetes
• low blood potassium
• or tuberculosis or other lung infection.
• Tell your doctor if you take beta
• blockers
• ketoconazole
• itraconazole
• erythromycin
• ritonavir or cobicistat
• other corticosteroids
• diuretics or other bronchodilators.
• Do not stop suddenly
• if breathing gets worse
• see your doctor. Contact a doctor if blurred vision occurs.
• Ask your doctor before use if pregnant or breastfeeding.