Bioflor 250 mg (sachet)

Indication

Treatment of acute infectious diarrhoea in adults and children; prevention and treatment of antibiotic-associated diarrhoea and colitis; in addition to vancomycin or metronidazole to prevent recurrence of Clostridium difficile disease; prevention of tube-feeding associated diarrhoea; treatment of irritable bowel syndrome.

Ingredients

• Saccharomyces boulardii CNCM I
• 745 250 mg per sachet (lyophilised yeast cells)

Direction

Oral route. 1 to 2 sachets, given once or twice daily. Mix the powder with a little water or a cool/lukewarm drink or soft food; do not mix with very hot, iced or alcoholic drinks.

Side effects

• Occasionally bloating
• flatulence or constipation
• Rarely allergic reactions such as rash or itching
• Very rarely fungaemia in patients with a central venous catheter or who are critically ill or immunocompromised
• Consult a doctor or pharmacist if side effects persist or are severe.

Precautions

• Do not use in patients with a central venous catheter
• critically ill or immunocompromised patients
• Do not open sachets near patients with a central line (risk of airborne contamination)
• Contains live yeast: do not mix with very hot
• iced or alcoholic drinks
• antifungal medicines reduce its effect
• In children and in severe or persistent diarrhoea
• rehydration is essential
• consult a doctor if diarrhoea lasts more than 2 days or there is fever
• blood in stools or vomiting
• Consult a doctor or pharmacist before use and stop if irritation or allergy occurs.