Laroxyl 25mg

Indication

Laroxyl 25 mg (Amitriptyline) is a tricyclic antidepressant used for the treatment of major depressive disorder, neuropathic pain, migraine prophylaxis, and nocturnal enuresis in children.

Ingredients

• Amitriptyline Hydrochloride 25 mg

Direction

Adults (depression): Initially 25–75 mg daily in divided doses or as a single dose at bedtime. Dose may be increased to 150–200 mg per day under medical supervision. Elderly: Start at lower doses (10–25 mg at night). For neuropathic pain: 10–75 mg at night. Take as directed by prescriber.

Side effects

• Drowsiness
• sedation
• dizziness.
• Dry mouth
• blurred vision
• constipation
• urinary retention (anticholinergic effects).
• Tachycardia
• palpitations.
• Weight gain.
• Postural hypotension.
• Confusion (especially in elderly).
• Rare: serious cardiac arrhythmias
• particularly in overdose.

Precautions

• Contraindicated in recent myocardial infarction
• arrhythmias
• and severe hepatic impairment.
• Contraindicated with MAO inhibitors — allow at least 14 days between treatments.
• Risk of QT prolongation and cardiac arrhythmias.
• Use with caution in patients with epilepsy
• glaucoma
• urinary retention
• or thyroid disease.
• May impair alertness — avoid driving or operating machinery.
• Risk of suicidal ideation in early treatment
• especially in young adults — monitor closely.
• Do not stop abruptly — taper gradually.
• Use with caution in pregnancy and breastfeeding.