Augmentin 625 mg

Indication

Augmentin 625 mg (Amoxicillin 500 mg + Clavulanic acid 125 mg) is a broad-spectrum penicillin antibiotic used in adults and children (≥40 kg) for the treatment of bacterial infections including community-acquired pneumonia, acute bacterial sinusitis, acute exacerbation of chronic bronchitis, otitis media, urinary tract infections, and skin/soft tissue infections.

Ingredients

• Amoxicillin
• Clavulanic Acid

Direction

Adults and children ≥40 kg: One 625 mg tablet every 8 or 12 hours (8-hourly dosing for moderate-severe infections; 12-hourly for mild infections). Take with food to reduce gastrointestinal side effects. Complete the full prescribed course.

Side effects

• Diarrhoea
• nausea
• vomiting — very common.
• Abdominal pain — common.
• Skin rash
• urticaria — common.
• Candidal overgrowth — common.
• Elevated liver enzymes
• hepatitis — uncommon.
• Anaphylaxis — rare but serious.

Precautions

• Do not use if allergic to penicillins
• cephalosporins
• or beta
• lactam antibiotics.
• Can cause serious hypersensitivity reactions including anaphylaxis.
• Use with caution in renal impairment — dose interval adjustment required.
• May cause Clostridioides difficile
• associated diarrhoea.
• Monitor liver function
• hepatotoxicity reported (especially in older males).
• May reduce efficacy of oral contraceptives.
• Keep out of reach of children.