GABIX 100mg 100mg

Indication

GABIX 100 mg (gabapentin) is an anticonvulsant used as adjunctive therapy for partial seizures with or without secondary generalisation in adults and children over 6 years. It is also used for the treatment of peripheral neuropathic pain (diabetic neuropathy, post-herpetic neuralgia) in adults.

Ingredients

• Gabapentin

Direction

Epilepsy (adults and children over 12 years): Starting dose 300 mg on Day 1, 300 mg twice daily on Day 2, 300 mg three times daily on Day 3. Maintenance: 900–3,600 mg/day in 3 divided doses. Neuropathic pain (adults): 300 mg on Day 1, titrated up to 1,800 mg/day in 3 divided doses. Dose reduction required in renal impairment.

Side effects

• Somnolence
• dizziness
• and fatigue (most common).
• Ataxia and coordination problems.
• Nystagmus.
• Weight gain.
• Peripheral oedema.
• Nausea and vomiting.
• Rare: serious skin reactions
• suicidal ideation.

Precautions

• Do not stop abruptly — taper dose to avoid withdrawal seizures.
• May cause somnolence
• dizziness
• and ataxia — do not drive or operate machinery until effects are known.
• Use with caution in patients with renal impairment — dose adjustment required.
• Potential for misuse and dependence has been reported.
• Risk of suicidal ideation — monitor patients
• especially at initiation.
• Avoid use with opioids — increased risk of respiratory depression.
• Keep out of reach of children.