Tranex 500mg/5ml

Indication

Tranex (Tranexamic Acid 500 mg/5 mL injection) is an antifibrinolytic agent used to prevent or reduce bleeding in surgical procedures, trauma, heavy menstrual bleeding (menorrhagia), and hereditary angioedema. It works by inhibiting plasminogen activation, thereby reducing fibrinolysis.

Ingredients

• Tranexamic Acid

Direction

Adults (IV/IM): Typically 500–1000 mg (5–10 mL) administered slowly intravenously two to three times daily, or as directed by a physician. Rate of IV injection should not exceed 1 mL/min to avoid hypotension. Dose and duration should be individualised based on indication.

Side effects

• Nausea
• vomiting
• diarrhea
• Hypotension with rapid IV injection
• Dizziness
• Thromboembolic events (rare)
• Allergic skin reactions (rare)
• Visual disturbances with prolonged use

Precautions

• Do not use if allergic to tranexamic acid.
• Contraindicated in patients with active thromboembolic disease or history of thrombosis.
• Contraindicated in subarachnoid haemorrhage.
• Use with caution in patients with renal impairment
• dose reduction may be required.
• May cause visual disturbances with long
• term use
• discontinue and seek ophthalmological assessment if this occurs.
• Use with caution with hormonal contraceptives (increased thrombotic risk).
• Inject slowly to minimise risk of hypotension.
• Keep out of reach of children.