Pelinol Not available

Indication

Pelinol (Salbutamol + Theophylline) is a bronchodilator combination used to relieve and prevent bronchospasm in asthma, chronic obstructive pulmonary disease (COPD), and other obstructive airway diseases. Salbutamol acts as a beta-2 adrenergic agonist while theophylline provides additional xanthine-based bronchodilation.

Ingredients

• Salbutamol
• Theophylline

Direction

Not available

Side effects

• Tremor
• palpitations
• tachycardia (salbutamol)
• Nausea
• vomiting
• headache
• insomnia (theophylline)
• Anxiety
• restlessness
• Hypokalaemia with high doses of salbutamol
• Arrhythmias at high theophylline levels

Precautions

• Do not use if allergic to salbutamol
• theophylline
• or related compounds.
• Use with caution in patients with cardiac arrhythmias
• hypertension
• hyperthyroidism
• or diabetes.
• Theophylline has a narrow therapeutic index
• monitor plasma levels and avoid interacting drugs (e.g.
• ciprofloxacin
• erythromycin
• cimetidine).
• May cause paradoxical bronchospasm
• discontinue immediately if this occurs.
• Use with caution in the elderly.
• Avoid in patients with uncontrolled seizure disorders.
• Keep out of reach of children.