RABESOV-L 20 mg / 75 mg

Indication

Treatment of gastroesophageal reflux disease (GERD), peptic ulcer disease, and related dyspeptic symptoms. Rabeprazole is a proton pump inhibitor that reduces gastric acid secretion; levosulpiride is a prokinetic and antiemetic agent that improves gastric motility.

Ingredients

• Rabeprazole Sodium
• Levosulpiride

Direction

Adults: One tablet (Rabeprazole 20 mg + Levosulpiride 75 mg) once daily, preferably 30 minutes before the morning meal or as directed by the physician.

Side effects

• Headache
• Diarrhoea
• Nausea
• Abdominal pain
• Flatulence
• Dizziness
• Extrapyramidal symptoms (tremor
• muscle stiffness) — levosulpiride related
• Hyperprolactinaemia (galactorrhoea
• menstrual disturbances)

Precautions

• Contraindicated in patients with prolactin
• dependent tumours.
• Levosulpiride may cause tardive dyskinesia or extrapyramidal effects with prolonged use.
• Avoid in patients with gastrointestinal obstruction
• perforation
• or haemorrhage.
• Use with caution in patients with severe renal or hepatic impairment.
• Rabeprazole may reduce absorption of drugs that require an acidic environment (e.g.
• ketoconazole
• iron salts
• atazanavir).
• Long
• term PPI use may be associated with hypomagnesaemia and increased risk of bone fractures.
• Keep out of reach of children.